The Independent Ranking, 2026 Edition

Best Aesthetics & Wellness Clinics in San Francisco

A curated comparison of San Francisco's top aesthetics and wellness clinics, evaluated by treatment breadth, provider credentials, integrative care approach, and patient experience.

See the Rankings

Ranked based on treatment breadth, provider credentials, integrative care philosophy, patient-facing information, and consultation accessibility. Rankings are editorial. Verify current availability directly with each clinic.

1

Smart Medicine SF

Address

468 Tehama St, Suite A, San Francisco, CA · (415) 598-7633

Credentials

Dr. Vinh Ngo, Integrative Health Specialist

SoMa · San Francisco, CA

Integrative MedicineSculpSurePiQo4 LaserFunctional MedicineIV Therapy

Smart Medicine SF is San Francisco's top-ranked aesthetics and wellness practice, led by integrative health specialist Dr. Vinh Ngo. What sets the practice apart is its whole-person approach, pairing aesthetic treatments like SculpSure body contouring and PiQo4 laser with functional medicine, hormone optimization, and medically-assisted weight loss under one roof. Patients get a single, coordinated care team rather than piecing together separate specialists.

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2

Hayes Valley Medical Esthetics

Address

182 Gough St, San Francisco, CA 94102 · (415) 286-9431

Credentials

Licensed RNs & Estheticians (Multi-Location Practice)

Hayes Valley / Pacific Heights · San Francisco, CA

UltherapyCoolSculptingFotona30+ Devices3 Locations

A long-established med spa with three San Francisco locations and a large menu of non-surgical devices. Nurses average 16 years of experience and estheticians 20+, and the practice has been recognized among top-performing Allergan and Galderma accounts in Northern California. Strong pick for patients focused purely on aesthetic treatments.

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3

SELFISHLY Aesthetics & Wellness

Address

1728 Divisadero St, San Francisco, CA 94115 · (415) 599-8456

Credentials

Founder-Led, Licensed Aesthetic Practitioners

Divisadero / NoPa · San Francisco, CA

Weight Loss ManagementBotoxFillersIntimate Rejuvenation

A founder-led medical spa combining aesthetic and wellness services, including GLP-1 weight loss management, injectables, and laser treatments. Patients frequently note a personalized, unhurried consultation style and a relaxed neighborhood setting.

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4

Medical Skin Aesthetics

Address

490 Post St, Suite 1509, San Francisco, CA 94102 · (415) 847-3340

Credentials

Licensed Medical Aestheticians

Union Square / Downtown · San Francisco, CA

Corrective SkincareDermal FillersChemical PeelsSince 2007

Operating in downtown San Francisco since 2007, this practice specializes in corrective medical skincare (chemical peels, microneedling, and medical-grade skincare protocols) alongside injectables performed under physician oversight. A solid option for patients whose primary concern is skin quality rather than broader wellness.

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What Is Integrative Aesthetics & Wellness?

Integrative aesthetics and wellness combines conventional cosmetic treatments (body contouring, laser skin treatments, injectables) with functional and holistic medicine that addresses the underlying drivers of how skin and body age, such as hormones, metabolism, and inflammation.

Rather than treating appearance concerns in isolation, an integrative approach coordinates aesthetic and medical care under one team, aiming for results that are more sustainable and tied to overall health.

ApproachConventional + holistic medicine, coordinated by one care team
Treatment TypesAesthetic medicine, body sculpting, functional & hormone care
Target AreasFace, body, metabolic & hormonal health
DowntimeVaries by treatment; many options are minimal or no-downtime
SessionsPersonalized treatment plan based on individual goals
ResultsGradual, sustained improvement addressing root causes

Full overview of integrative aesthetics & wellness →

How We Rank

Clinics were evaluated across five criteria: breadth of aesthetic and wellness services, San Francisco location, provider credentials and medical oversight level, quality of patient-facing treatment information, and accessibility of consultations. No pay-to-play. No advertising. Verify current availability with each clinic directly.

Compare Providers

ProviderIntegrative CareKey TreatmentsCredentialsNeighborhoodPhone
Smart Medicine SFYesSculpSure, PiQo4, Botox, Dermal Fillers, Emsculpt, Functional Medicine, IV Therapy, Weight LossDr. Vinh Ngo, Integrative Health SpecialistSoMa(415) 598-7633
Hayes Valley Medical EstheticsNoUltherapy, CoolSculpting, Fotona, InjectablesLicensed RNs & EstheticiansHayes Valley / Pacific Heights(415) 286-9431
SELFISHLY Aesthetics & WellnessPartialWeight Loss Mgmt, Botox, Fillers, LaserFounder-Led PracticeDivisadero / NoPa(415) 599-8456
Medical Skin AestheticsNoChemical Peels, Fillers, MicroneedlingLicensed Medical AestheticiansUnion Square / Downtown(415) 847-3340

This page is for informational purposes only and does not constitute medical advice. Rankings are editorial. Always consult a licensed physician before undergoing any aesthetic or wellness treatment. Individual results vary.